Cardiac Reconstructions with Allograft Tissues by Hopkins, R. A.

By Hopkins, R. A.

This instruction manual is a guide meant for citizens at any level in their adventure, together with cardiothoracic fellowship. it truly is intended as a tenet to appreciate the pathophysiologic reason of motion within the working room and extensive care unit. Emphasis is put on body structure, anatomy, pathology, clinical administration, and surgical process.

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Cardiac Reconstructions with Allograft Tissues

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C. K. 2, 31 and 56 months after operation, each being successfully managed with intravenous antibiotic therapy. 15,16 In summary, the UAB cryopreserved homograft valve experience supports the concept that the homograft aortic valve offers a number of special features that make it an attractive replacement device for many patients with aortic valve and aortic root disease. References 1. Ross DN. Homograft replacement of the aortic valve. Lancet 1962;2:487. 2. Kirklin JK, Smith D, Novick W, et al.

Patient status 10 or more years after ‘fresh’ homograft replacement of the aortic valve. Circulation 1984;70:I182–I186. 29. Stelzer P, Elkins RC. Pulmonary autograft: An American experience. J Carciac Surg 1987;2: 429–433. 1. Homograft Valves: Historical Perspective 30. Miller DC, Shumway NE. “Fresh” aortic allografts: long-term results with free-hand aortic valve replacement. J Card Surg 1987;2:185–191. 31. Thompson R, Ahmed M, Seabra-Gomes R, Ilsley C, Rickards A, Towers M, Yacoub M. Influence of preoperative left ventricular function on results of homograft replacement of the aortic valve for aortic regurgitation.

Homograft Valves: Historical Perspective Summary Beginning in 1962 there have been four eras related to method of procurement, sterilization, and storage of aortic valve homografts. During the first era, fresh aseptic harvesting with immediate transplantation (within hours or a few days—“fresh fresh”) was the rule. This method appears to have given excellent results, both initially and in terms of long-term durability. The second era consisted of a clean harvest with harsh sterilization and storage techniques, clearly resulting in poor durability.

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